Tramadol is a painkiller, that has been shown to be effective in the treatment of premature ejaculation in men – European clinical trials have shown.

Pharmaceutical company Ampio

The drug manufacturer, claims that the results of the research have been so encouraging that it will be able to apply for admission to the market. The preparation called Zertane has the advantage that you do not need to use it every day, as some medicines for premature ejaculation. Just use it before the planned sexual intercourse. Professor Zbigniew Lew-Starowicz, a sexologist, told PAP that he does not expect a breakthrough in the treatment of premature ejaculation in men after the introduction of this drug, because he is already well-treated with available antidepressants.

“These are preparations of the so-called serotonin reuptake, often used to treat depression, but also useful in men suffering from premature ejaculation” – explained the professor. He added that the majority of antidepressants need to be taken every day, but there is a drug of this type available in Poland, which can be used only before intercourse to delay ejaculation.

The active substance of Zertane is tramadol, a synthetic opioid with weaker effects and less potential for addiction. It also affects the reuptake of serotonin and noradrenaline, which enhances the analgesic effect, but also reduces the intensity of the tactile feedback received.

In the treatment of premature ejaculation, lidocaine, a painkiller used for procedures under local anesthesia, has also been used for several years. However, it is cumbersome to use, because it is used in the form of ointments. “Such measures require the use of a condom, because at the same time, they may weaken the feeling of sexual stimuli in a partner” – emphasized prof. Lew-Starowicz.

Advanced research is also conducted on a drug containing lidocaine and an admixture of prilocaine, an anesthetic with less toxic effects than lidocaine. Both substances are used in one preparation in the form of ointments for local anesthesia. In the treatment of premature ejaculation they have to be available in a spray.